Replacement For Viagra is Stendra, FDA Approves Stendra

FDA has approved new erectile dysfunction drug developed by Vivus. The drug has been named as Stendra.

With this development, Vivus has finally managed to get first approval for its product. The approval came in time when patent of Viagra is about to expire. Stendra is expected to be replacement for Viagra. The drug manufacturer is also hoping approval for its weight loss drug called Qnexa which is in reviewal process.

Stendra is brand name of Avanafil. Earlier we had reported development of Avanafil, and the drug has got approvalfrom FDA. Currently there are three FDA approved erectile dysfunction drug treatments namely, Viagra; Cialis; Levitra. Generic Viagra is most popular drug. Being top popular drug, pharmaceutical companies were competing to take place of Viagra when its patent expires.

What is Erectile Dysfunction?

Erectile Dysfunction is a disorder characterised as a man is unable to get erection or maintain erection or erection is not rigid enough for sexual intercourse. FDA estimates around 30 million suffering by erectile dysfunction caused by various reasons.

How Stendra Works?

Like other drugs, Stendra also works by increasing blood flow in penis which eventually results in erected penis.

How To Take Stendra for Best Effect?

Stendra is recommended to take half an hour before intercourse. Medical experts have seen Stendra producing effect within fifteen minutes. The time of action is maximum and can be less for other patients. Stendra is thus the fastest acting erectile dysfunction drug.

Stendra Side Effects

FDA has strictly advised patients not to take Stendra if patient is taking nitrate drug. Stendra is contraindicated to nitrate drugs and may lower blood pressure. Side effects reported by FDA are vision problem. Since Stendra is also PDE5 inhibitor drug it can cause vision loss in single or both eyes. Hearing problem is another side effect likely to develop in some patients.

Headache, nasal congstion, redness at several parts of body and back pain are common side effects observed by FDA review panel.

Effects of Hypertension on Sex Life

Elevating or fluctuating blood pressure can modify the risk factors of cardiovascular diseases and mortality. There is a mutual relation between swinging blood pressure and hyper tension. The case is similar when it comes to hypertension and sexual difficulties. Hypertension can impact your sex life. Although they don’t have any signs or symptoms, but the impact on sex life can be majorly experienced. Hypertension can affect your overall sexual satisfaction. A link between high blood pressure and sexual problems is generally the major factor that affect men's sexual health.

Hypertension damages the lining of your blood vessels and causes the arteries to harden and narrow, this then blocks the blood flow towards the male reproductive organ and the man then faces difficulty in maintaining and sustaining erection for the desired period of time. Coming to females, hypertension can reduce the blood flow to the vagina, which may result in decrease in the sexual desire or arousal. It may also lead to difficulties in achieving orgasm. If this case is experienced, consult a doctor and get the necessary treatments before getting the case worsened.

Erectile Dysfunction Indicates Future Heart Disease

A research study has confirmed Vasculogenic ED as marker for future cardiovascular disease. Presence of Vasculogenic indicates that a person is going to have heart disease.

Many earlier studies have established close link between erectile dysfunction and cardiovascular disease but failed to explain how exactly. The latest one has provided confirm proof that a biological marker is something that is responsible for heart diseases in patients who are suffering from erectile dysfunction.

Lead researcher of the study, Dr Kew Kim Chew says, the study has provided pathological evidence of connection on how atherosclerosis develops from endothelial dysfunction. Dr Chew is physician and senior clinical researcher at Keogh Institute for Medical Research.

Endothelial dysfunction is pathological status of membrane lining inside blood vessels. It is the status basically means imbalance in contraction and widening of blood vessels.

In both erectile dysfunction and cardiovascular disease, dysfunction of endothelium is caused by higher concentration of biomarkers (such as cytokines interleukin-6, interleukin-8 and 18) in plasma. Also high level of C-reactive proteins has also been noticed in both the condictions.

This way erectile dysfunction deomnstrates vascular disease in penile muscles. That is the reason that ED medicines such as viagra helps in heart diseases also.

Although ED may get developed because of psychological (anxiety, stress and depression) and neurological disorders, vascular disorder is more common cause. Vascular cause in more observed in young adults with liklihood of developing heart disease in future.

Erectile Dysfunction Drugs Safer for Diabetics- Says Report

Erectile dysfunction is a problem that has devastated the conditions of many. The disease is such that there are drugs to fight it (viagra, cialis or Kamagra), but these drugs end up leaving several side effects in the body. There are mild speculations that do the round that erectile dysfunction drugs have ill effects on patients with diabetics. However, a recent study has shown that ED drugs are safe for diabetic patients. This study has been really beneficial for several people with diabetics and for doctors who have been reluctant to prescribe diabetes medicines to patients.

Dr Moshe Vardi, M.D., with the internal medicine division at Lady Davis Carmel Medical Center in Israel said that observation has not come as surprise to them but provides support to the notion that this class of drug is efficient and secure for a specific class of people. The medications that are available are considered the basis of treatment for erectile dysfunction for the general populace. However, patients with diabetes are more likely to variations in the results of these drugs as they have various complications and the process of their erectile dysfunction are multifactorial, thus making their treatment a almost a challenge for physicians and health care professionals.

An international organization called The Cochrane Collaboration conducted a research that included the around 1,700 men who had diabetes. The men varied in age, ethnicity and weight. After the 12 week study it was found that about 30 percent of men were reported with massive improvement in their sex life and no reported were found that had any type of complications related to diabetes.

Now Genetic Signals Will Decide, Whether You have Cancer

As per the latest researches done by scientists from Virginia Bioinformatics institution (VBI) have developed a new technology that will help by detecting genetic changes that will differentiate patients of cancer from healthy people. The technology is as per the recent studies published in the journals. The detections will one day serve as the best cancer predisposition test. Our blood cells have majority of non coding DNA. This means the ones that are not set down as proteins. Microsatellites are the specific category of these junk DNA. A human genome consist of two million satellite repeats, however, these repeats vary depending on the person. The most of its usage is made in forensic and paternity tests.

The VBI researches in Dec 2010 discovered a four nucleotide repeat (AAAG) in a particular gene called estrogen related receptor gamma (ESRPG). This is a very powerful gene that indicates the susceptibility of breast cancer through an individual’s genetic. The repetitive micro satellite DNA is much more present in cases of breast cancer. Similarly, patients with increased number of these repeats in the supporter areas of the ESPRG gene have the risks of three fold higher cancer susceptibility as compared to healthy people.

However when the latest studies were carried out, scientists instead of emphasizing on a single gene , they created a design for a fresh DNA micro array which allowed them to calculate more than 2 million of microsatellites in the human genome within a single experiment.

In the recent days, cancer has been one of the most widely observed fatal health conditions in people. Inventions of these finest technologies have made it the best attempt to convert its criticalities in to normal. With such an invention pace, soon we can take benefits of many more such technologies that would further lessen the troubles and would serve guarantee of the dreaded disease to be cured.

Injectable ED Medicine, Caverject, Recalled

Erectile dysfunction, a disorder in men that affects their sexual as well as overall health has been concerning men. Initially, it was associated with ageing in men. These days however we notice even young men suffering from impotence where physical weakness or psychological problems can be the factors that are the causes that put men‘s virility to a risk. While the pharmacy industry offers us a wide range of options today to get ourselves treated, injections have surely been one of them.

Caverject offers the injection therapy for men suffering for erectile dysfunction as it is claimed that injection therapy can be one of the best forms of therapy according to the American Urological Association (AUA). These shots can enable you to have an erection within 20 minutes which makes many men prefer these shots to the oral pills such as viagra or Kamagra

News recently about Caveject however states that Pfizer has recalled for these shots as they seem to be defective. Around 12 batches of these shots have been put for further checking and analysis to consider if the needles are actually defective. It has been noticed that the blockages in the needle can actually put one at risk and thus the U.K healthcare products Regulatory Agency has issued an alert stating that the breaking of a needle can have adverse effects on one. It has also asked for these defective shots to be replaced. Since the needles are manufactured by Becton Dickinson & Co (BDS), they might also be questioned. There has been no information available from the spokesperson that has declined the news. These injections have been introduced when before the invention of pills.

Avanafil, More Effective and Safer Than Other ED Drugs

A pharmaceutical company Vivus Inc, is experimenting a new erectile dysfunction drug which is believed to be more effective than other impotence drugs such as viagra, cialis and kamagra. Company has claimed that the new drug has worked in more than 80% men, unlike viagra which is believed to be working in some men.
Representatives of Vivus Inc are about to meet concerned US FDA department for the approval application and process for their new weight-loss drug named as Qnexa.

Weight loss and impotency drug categories have huge market across the glob. Vivus Inc is trying to capture big chunk of the market by targeting these two drugs. So far, no drug has been successful like viagra.

Trial results of Avanafil were released in two parts. Latest release is an extended version of previous results of clinical trial. In second phase of trial patients were asked to continue drug after completion of first stage which lasted for a year.

Because Avanafil is metabolized fairly rapidly, men may be able to use it safely twice a day, at the beginning and end of the day, Tam said.

Unlike viagra, which is once a day drug, it is safe to take Avanafil twice a day as it is easy to metabolize. One can take it in morning and in evening as well.

US FDA had asked Vivus Inc to provide more data regarding heart issues and birth defects related to their weight loss drug called Qnexa.

Cialis (Tadalafil) – Erectile Dysfunction Medicine

Cialis is a brand name for the drug Tadalafil. It is FDA approved potent medication for treating erectile dysfunction. Food and Drug Administration of America has approved tadalafil for sale in the United States as the third erectile dysfunction treatment drug (after Viagra and Levitra). Cialis is an oral prescription medication for the treatment of men erectile and sexual dysfunction. Cialis is also known to be very effective in the treatment of pulmonary arterial hypertension.



Cialis Mechanism: How Cialis Works?
Cialis (Tadalafil) is a PDE5 inhibitor; a PDE5 inhibitor is a drug used to block the degradative action of phosphodiesterase type 5 on cGMP in the smooth muscle cells lining the blood vessels supplying the corpus cavernosum of the penis. The inhibition of phosphodiesterase type 5 (PDE5) enhances erectile function by increasing the amount of cGMP. In certain cases, there are also reports as regards vision impairment and sudden hearing loss.

Cialis Preparations
Cialis is available in a pill form; tablets in 5 mg, 10 mg and 20 mg doses are available. The tablets are yellow, film-coated, and almond-shaped. The approved dose for pulmonary arterial hypertension is 40 mg (two 20-mg tablets) once daily.

Availability of Cialis
Tadalafil drug is marketed by Lilly ICOS, LLC world-wide under the brand names Cialis and Adcirca. Adcirca, one of the brand that also includes tadalafil, is developed for the treatment of pulmonary arterial hypertension. Cialis is a prescription medication; it can be purchased only on the prescription from a registered medical practitioner. It is easily available across various registered online pharmacies or online chemist; it is a convenient way of buying as compared to the convention method of buying from drug stores. Many online pharmacies also offer attractive discounts and offers.

Cialis Side Effects
Cialis is not free from side effects, it is known for causing a number of side effects. The most common side effects when using tadalafil includes headache, backpain, muscle aches, flushing, indigestion and stuffy nose. Back pain and muscle aches can occur 12 to 24 hours after taking the drug. The other side effects usually go away after a few hours. Tadalafil is a PDE5 inhibitor; the PDE5 inhibitors are known for causing transiently low blood pressure (hypotension). For this reason, organic nitrates should not be taken for at least 48 hours after taking the last dose of tadalafil.

List of Erectile Dysfunction Treatment Options

Erectile dysfunction is referred to as male impotence. It is a condition where in a person is unable to develop or maintain erection in penis. According to a recent study, over 18 million men in US alone are struggling with this condition. Most men by age 45 have experienced erectile dysfunction at least some point of the time in life. It is believed that the condition not only disturbs the sexual but the day-day married life as well.

There are many causes for erectile dysfunction. It could be either physical, various underlying causes and psychological. Reduced blood flow to the penis and nerve damage is the most common physical causes. The other underlying causes include vascular diseases, diabetes, drugs, hormonal imbalance, neurological conditions, pelvic trauma, surgery, radiation, peyronie's disease, Venous leak and so on. A person suffering from any of the above could be affected with this condition.

Psychological causes also play a very important role in erectile dysfunction treatment. Depression, guilt, worry, stress and anxiety all contribute to loss of libido in men and give rise to this condition. Sex is a state of mind if there are situations around that can lead to stress and anxiety, definitely it’s going to affect libido in men. Psychological factors in impotence are often neglected by men, resulting in to aggravation of the condition.

Erectile dysfunction can be treated in many ways; however, the method of treatment depends on the ultimate underlying cause. If the situation is associated with various diseases and conditions lots of oral medication can be offered for the treatment of sexual problems such as Levitra, Cialis, Viagra and other. Some of these pills are available only by prescription; some can be easily bought without visiting a doctor. More serious problems might require injecting medicine into penis, vacuum pumps, surgery and in case of psychological issues, consulting sex counselors.

Most erectile dysfunction causes can be corrected with timely action and care. Hence, once the symptoms are experienced, it is advisable to visit a sexual counselor or some registered medical practitioner